The most common causes of QuickBooks Error 15227 are corrupt system files or payroll changes. It suggests that important system files are erratic or unresponsive. Software performance and payroll procedures may be affected by this issue. Repairing Windows files, updating QuickBooks, or setting up system preferences for optimal performance could all be part of the solution. Do you need assistance with QuickBooks? Call 1.855.738.2784 to talk to a professional.